Adenovirus Serotype 5 Vectors with Tyr3-Octreotate Modified as a Virulytic Oncotherapy Agent in AGS Cells
Background: Oncolytic viral therapy is known as a new promising strategy to treat cancer.Oncolyticviruses (OVs) can replicate in cancer cells, and besides this primary effect, OVs can also stimulate the immune system.Moreover, Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy.The present study aimed to make a chang